TRANSLATIONAL PHYSIOLOGY Hyperbilirubinemia modulates myocardial function, aortic ejection, and ischemic stress resistance in the Gunn rat
نویسندگان
چکیده
Bhavisha Bakrania, Eugene F. Du Toit, Kevin J. Ashton, Can J. Kiessling, Karl-Heinz Wagner, John P. Headrick, and Andrew C. Bulmer Heart Foundation Research Centre, Griffith Health Institute, Griffith University, Gold Coast, Queensland, Australia; Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia; and Department of Nutritional Science, University of Vienna, Vienna, Austria
منابع مشابه
Hyperbilirubinemia modulates myocardial function, aortic ejection, and ischemic stress resistance in the Gunn rat.
Mildly elevated circulating unconjugated bilirubin (UCB) is associated with protection against hypertension and ischemic heart disease. We assessed whether endogenously elevated bilirubin in Gunn rats modifies cardiovascular function and resistance to ischemic insult. Hearts were assessed ex vivo (Langendorff perfusion) and in vivo (Millar catheterization and echocardiography), and left ventric...
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تاریخ انتشار 2014